Sr. Systems Engineer

Sr. Systems Engineer ROCGJP00039025

• Hourly pay: $40-$50/hr
• Worksite: Leading biotechnology company (Pleasanton, CA 94588 - Onsite, May do an occasional travel to the Santa Clara jobsite for training, etc.)
• W2 Employment, Group Medical, Dental, Vision, Life, Retirement Savings Program, PSL
• 40 hours/week, 6 Month Assignment

A leading biotechnology company is seeking a Sr. Systems Engineer. The successful candidate will drive the feasibility, development, and integration of complex multi-disciplinary systems spanning sample preparation, library preparation, molecular detection technologies (e.g., digital PCR, sequencing by synthesis, microarray), and bioinformatics/data processing pipelines.

Sr. Systems Engineer Responsibilities:

• Systems Development, Integration & Analysis:
  • Drive system-level development activities across wet lab workflows, instruments, and data pipelines for next generation diagnostic solutions.
  • Perform hands-on system integration and troubleshooting of workflows including sample extraction, library preparation, molecular detections, and data transfer.
• Verification, Validation & On Market support:
  • Plan, design and execute verification and validation (V&V) test cases to ensure comprehensive coverage of requirements.
  • Analyze test results for accuracy, validity, and relevance to user needs.
• Collaboration & Influence:
  • Represent Systems Engineering in cross-functional project teams on key topics such as requirements management, defect management, system integration, etc.
  • Collaborate closely with assay scientists, software developers, hardware engineers, and bioinformaticians to align on end-to-end workflows.

Sr. Systems Engineer Qualifications:

• PhD degree with related field with 5+ years of relevant industry experience is highly valued.
• Master’s degree with 10+ years of relevant industry experience;
• Or a Bachelor’s degree with 10+ years of relevant industry experience.
• Major in Systems Engineering, Bioengineering, and Biomedical Engineering.
• hands-on industrial experience with sequencing related workflows, including nucleic acid extraction, library preparation, and sequencing.
• Proven lab troubleshooting experience in sequencing workflows and PCR-based workflows.
• Exposure to bioinformatics/data processing pipelines for sequencing output (variant calling, data QC) is highly desirable.
• Experience with statistical tools and DoE methodologies (JMP, regression, ANOVA) is required.
• Familiarity with system-level product development in life sciences instrumentation is a plus.
• Experience across multiple product life-cycle stages is a plus.
• Experience in digital PCR platforms is desirable.
• Experience with developing In-vitro Diagnostic products is desirable.
• Experience in implementing workflow on semiconductor based sensing devices or microfluidic devices is desirable.
• Scripting/programming experience (Python, R, or equivalent) is a plus.
• Translate complex scientific workflows into reliable, scalable system solutions.

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