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General Application

Want to join us but don't see your role listed? | Brisbane, CA or St. Louis, MO | Full Time

Job Description

At Arch Oncology, we are aiming high to discover and develop new antibody therapeutics to treat patients living with cancer. We are committed to advancing antibodies with best-in-class potential.

Our next-generation anti-CD47 antibodies are highly differentiated, with the potential to improve upon the safety and efficacy profile relative to other agents in this class. Our antibodies work by blocking the “don’t eat me” signal, the standard mechanism of anti-CD47 antibodies. Beyond blocking this signal, our antibodies also directly kill tumor cells. Importantly, our antibodies bind preferentially to tumor cells, instead of normal cells, and bind even more potently to tumors in their acidic microenvironment (low pH).

Expanding our fight against cancer, we are advancing our lead anti-CD47 antibody AO-176 into clinical development for the treatment of patients with solid tumors.

We are aiming high in our fight against cancer. We are a team of highly experienced and driven professionals who are committed to excellence in all that we do. Our leadership team has successfully developed new drugs before. We know what we need to do to collaborate and execute to get the job done.

If you share this commitment and want to work with a team that is focused on helping patients, come aim high with us and apply.

Office Locations:

At Arch Oncology, we have two bases. Our headquarters is in Brisbane, CA, a gateway of biotechnology innovation, and our scientific research laboratory is in St. Louis, MO - home of the Gateway Arch.

Career opportunities at Arch Oncology:

We are always looking for top talent to grow our high-performing team. While you may not currently see a specific job role that is a fit on our career page, we invite you to submit your resume and qualifications as new positions become available frequently and we will check our candidate database for possible matches.

We frequently have openings for the following roles/departments:

  • Research Scientist - St. Louis, MO

  • Clinical Team Openings - St. Louis, MO

  • Cancer Immuno-oncology Research and/or Clinical Drug Development - St. Louis, MO


Arch Oncology is an Equal Opportunity Employer and does not discriminate against applicants due to race, ethnicity, gender, veteran status, or on the basis of disability or any other federal, state or local protected class.