Vice President, Safety

About Allogene:

Allogene Therapeutics, with headquarters in South San Francisco, is a clinical-stage biotechnology company pioneering the development of allogeneic chimeric antigen receptor T cell (AlloCAR T™) products for cancer and autoimmune disease. Led by a management team with significant experience in cell therapy, Allogene is developing a pipeline of “off-the-shelf” CAR T cell product candidates with the goal of delivering readily available cell therapy on-demand, more reliably, and at greater scale to more patients. For more information, please visit www.allogene.com, and follow @AllogeneTx on X (formerly Twitter) and LinkedIn.

About the role:

Reporting directly to the Head of R&D/CMO, this leader will be responsible for the safety of our clinical work. You will work with the Clinical Development team in supporting our efforts in this exciting new area of cancer immunotherapy. This position is based out of our headquarters in South San Francisco, CA. We encourage applicants who believe they have the skills and drive to succeed at Allogene to apply for this role.

Responsibilities include, but are not limited to:

• Safety expert for product candidates
• Oversight of clinical trial safety including safety monitoring plan and data analysis
• Assess emerging safety data, ensure appropriate risk communication, and development of risk management/minimization strategies
• Pharmacovigilance strategy and implementation
• Aggregate safety reports, including DSURs, Health Authority SAE reporting and other safety aspects of regulatory filings
• Lead the safety team, provide necessary training and ongoing coaching, discipline and recognition of direct staff, including performing annual performance reviews
• Oversight of safety vendors
• Identify key areas for change and alignment and mobilize organization to make changes happen
• Influence and/or develop broad-based programs and initiatives to meet executive level vision and mission
• Collaborate with functional leaders to set strategy and shared objectives
• Accomplish results through the management of a team of managers, professional employees and/or other leaders
• Other duties as assigned

Position Requirements & Experience:

• MD or equivalent degree; completion of residency with industry experience in safety and pharmacovigilance; oncology experience required
• Global experience in clinical trial as well as post-marketing setting (oncology/cell therapy experience highly preferred but not required)
• Experience with global regulatory filings
• Excellent organizational skills and an ability to prioritize effectively to deliver results within aggressive timelines with the ability to work independently and as part of a team
• Strong interpersonal skills including verbal and written communication are essential in this collaborative work environment
• Ability to communicate with internal and external physicians to evaluate specific safety events
• Ability to evaluate CROs and other vendors that may assist Allogene in fulfilling safety oversight and reporting obligations
• Candidates must be authorized to work in the U.S

We offer a chance to work with talented people in a collaborative environment and provide a top-notch compensation and benefits package, which includes an annual performance bonus, equity, health insurance, generous time off (including 2 annual holiday company-wide shutdowns) and much more. The expected salary range for this role is $320,000 - $380,000. Actual pay will be determined based on experience, qualifications, geographic location, business needs, and other job-related factors permitted by law.

As an equal opportunity employer, Allogene is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job-related characteristics or other prohibited grounds specified in applicable federal, state and local laws. We also embrace differences in experience and background, and welcome diversity of opinions and thought with active recruitment and internships designed to create a stronger and better Allogene that is focused on developing life-changing products for patients.

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