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Senior Director, Portfolio and Program Management

Clinical Program Management | Hybrid in South San Francisco, CA | Full Time | From $230,000 to $270,000 per year

Job Description

About Allogene:

Allogene Therapeutics, with headquarters in South San Francisco, is a clinical-stage biotechnology company pioneering the development of allogeneic chimeric antigen receptor T cell (AlloCAR T) products for cancer and autoimmune disease. Led by a management team with significant experience in cell therapy, Allogene is developing a pipeline of “off-the-shelf” CAR T cell product candidates with the goal of delivering readily available cell therapy on-demand, more reliably, and at greater scale to more patients.

About the role:

We are looking for a talented, motivated Senior Director to join our Portfolio & Program Management Team as a key leader for our lead program. You will be responsible for actively managing a highly technical, cross functional team to drive program execution. As the lead Program Manager, you must be proactive, adaptable, and thrive in a dynamic, collaborative environment. You will manage program scope, timelines, deliverables, budget, risks, decisions and communications. This is a hybrid role based at our headquarters in South San Francisco, CA (US based remote may be considered as well for candidates outside of the area).

Responsibilities include, but are not limited to:

  • Lead a cross-functional program team (including representatives from Research, Clinical, Regulatory, Ops Tech, and Commercial) to manage the development and execution of program strategy in alignment with corporate goals
  • Have accountability as the primary contact for the program, including ownership, maintenance, and communication of all program information, including strategy, scope, deliverables, timelines, status and key risks
  • Work with the program team members to facilitate project/program execution from Pre-IND planning through BLA/MAA approvals utilizing project management tools and processes to maintain strategic direction, project schedule/timeline, communications, budget/cost and identify and mitigate risks
  • Facilitate program related decision-making processes by working with the program teams to develop and present analyses and recommendations to senior management as part of the governance process
  • Leverage input from all critical functions to prepare detailed integrated development plans that maximize the value of the programs. Define critical path activities/decisions and associated risks, in collaboration with program teams, to ensure the programs meet their milestones on time and on budget
  • Manage program team meeting operations including planning agendas, scheduling meetings, preparing minutes, and following up with team members on critical action items
  • Ensure program team activities and decisions are clearly communicated, documented, and archived
  • Foster strong relationships and support effective and impactful communications with management, team members and functional line managers to facilitate timely and active management of issues/risks/decisions/opportunities
  • Maintain program-related documentation such as program plans, budget and timelines and project goals
  • Participate as a member of the Portfolio & Program Management Team to continually improve on program management and governance processes, as well as bring best practices to teams across the organization
  • Other duties as assigned

Position requirements & experience:

  • Bachelor’s Degree in life sciences or related field required (or relevant experience) with at least 12 years of project management experience in similar role in the biotechnology industry and at least 5 years in a leadership role
  • Cell therapy experience strongly preferred
  • Self-starter with demonstrated leadership skills
  • Excellent organizational skills and an ability to prioritize effectively to deliver results within reasonably established timelines
  • Ability to work independently and as part of a team
  • Strong interpersonal skills including verbal and written communication are essential in this collaborative work environment
  • Candidates must be authorized to work in the U.S.


We offer a chance to work with talented people in a collaborative environment and provide a top-notch compensation and benefits package, which includes an annual performance bonus, equity, health insurance, generous time off (including 2 annual holiday company-wide shutdowns) and much more. The expected salary range for this role is $230,000 to $270,000 per year. Actual pay will be determined based on experience, qualifications, geographic location, business needs, and other job-related factors permitted by law.

As an equal opportunity employer, Allogene is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job-related characteristics or other prohibited grounds specified in applicable federal, state and local laws. We also embrace differences in experience and background, and welcome diversity of opinions and thought, designed to create a stronger and better Allogene that is focused on developing life-changing products for patients.


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